Used by over 3 million people annually, this is the most popular non-surgical treatment to reduce wrinkles. This benefit comes from the drug’s ability to selectively and precisely relax the muscle which causes the wrinkle to occur. Wrinkles that form with the movement of facial muscles and disappear when the face is at rest are called dynamic wrinkles. These wrinkles are effectively resolved with Botox® therapy. Wrinkles that persist when the face is at rest, or static wrinkles, will also often dramatically improve, or even disappear in time. These will sometimes need other adjunctive treatment, though, for optimal results.